An oxidation experiment for a first-year organic chemistry class is presented. This oxidation utilizes a solid mixture of CuSO4•5H2O and KMnO4 prepared by mortar and pestle. The oxidations take place under solvent-free conditions and near quantitative yields are obtained for the reactions. Thin-layer chromatography is used to monitor the progress of the reaction. This experiment provides for the simple oxidation of a secondary alcohol to a ketone using a relatively nontoxic oxidizing agent under solvent-free conditions.
Esteb, John J.; Schelle, Michael W.; and Wilson, Anne N., "A Solvent-Free Oxidation of Alcohols in an Organic Laboratory" / (2003): -.
Available at http://digitalcommons.butler.edu/facsch_papers/606