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Abstract

Post-Traumatic Stress Disorder (PTSD) presents a significant challenge in mental health treatment, affecting millions of individuals worldwide. While conventional therapies such as cognitive behavioral therapy and selective serotonin reuptake inhibitors have shown some efficacy, a considerable portion of patients remains resistant to treatment. Recent clinical trials have demonstrated the safety and efficacy of MDMA-assisted psychotherapy leading to the Food and Drug Administration's designation of Breakthrough Therapy status and the submission of a New Drug Application. Despite promising results, challenges such as stigma, regulatory barriers, and therapist training remain. However, the need for innovative treatments for PTSD necessitates further exploration of MDMA-assisted psychotherapy's therapeutic potential.

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