Insular Cortex Lesions and Morphine-Induced Suppression of Conditioned Stimulus Intake in the Rat
The present experiment examined the influence of insular cortex (IC) lesions on the intake of a taste stimulus in a consummatory procedure that used morphine as the unconditioned stimulus. In normal rats, morphine caused a rapid reduction in saccharin intake when the taste was novel but not when it was familiar. Irrespective of stimulus novelty, morphine had little influence on the saccharin consumption of IC-lesioned rats. The results are discussed in terms of a lesion-induced disruption of (i) a reward comparison mechanism and (ii) the perception of taste novelty.
Copyright © 2009 American Psychological Association.
This is a post-print version of an article originally published in Behavioral Neuroscience, 2009, Volume 123, Issue 1.. The version of record is available through: American Psychology Association. "This article may not exactly replicate the final version published in the APA journal. It is not the copy of record."
Roman, Christopher T. and Reilly, Steve, "Insular Cortex Lesions and Morphine-Induced Suppression of Conditioned Stimulus Intake in the Rat" (2009). Scholarship and Professional Work – COPHS. 167.