The present study was designed to examine whether lesions of the insular cortex (IC; Experiment 1), the basolateral amygdala (BLA) or medial amygdala (MeA; Experiment 2) influence the neophobic reactions to orally consumed liquid stimuli. Three different types of stimuli were used: taste (0.5% saccharin), olfactory (0.1% amyl acetate), and trigeminal (0.01 mM capsaicin). Rats with IC, BLA and MeA lesions showed normal responses to the olfactory and trigeminal stimuli. Each type of lesion, however, disrupted the initial occurrence of neophobia to the taste stimulus. The significance of these findings to conditioned taste aversion is discussed.
This is a post-print version of an article originally published in Brain Research, 2009, Volume 1251, pp. 195-203..
The version of record is available through: Elsevier.
Lin, Jian-You; Roman, Christopher T.; St. Andre, Justin; and Reilly, Steve, "Taste, Olfactory and Trigeminal Neophobia in Rats with Forebrain Lesions" (2009). Scholarship and Professional Work – COPHS. 168.