The Journal of Family Practice
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YES. Antibiotic use reduced mortality and treatment failure in patients hospitalized with acute exacerbations of chronic obstructive pulmonary disease (COPD) (strength of recommendation [SOR]: A, systematic reviews of randomized controlled trials [RCTs]).
Giving antibiotics early to hospitalized patients decreased the need for later ventilation and readmission within 30 days for exacerbation of COPD (SOR: B, a retrospective cohort study).
Mathew, Sagi; Zeitlin, Deborah S.; and Rickett, Katherine, "Do Antibiotics Improve Outcomes for Patients Hospitalized with COPD Exacerbations?" (2012). Scholarship and Professional Work – COPHS. 183.