Genomic context and TP53 allele frequency define clinical outcomes in TP53-mutated myelodysplastic syndromes, Guillermo Montalban-Bravo, Rashmi Kanagal-Shamanna, Christopher B. Benton, Caleb A. Class, Kelly S. Chien, Koji Sasaki ,, Kiran Naqvi, Yesid Alvarado, Tapan M. Kadia, Farhad Ravandi, Naval Daver, Koichi Takahashi, Elias Jabbour, Gautham Borthakur, Naveen Pemmaraju, Marina Konopleva, Kelly A. Soltysiak, Sherry R. Pierce, Carlos E. Bueso-Ramos, Keyur P. Patel, Hagop Kantarjian, Guillermo Garcia-Manero
Caleb Class

Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes, Guillermo Montalban-Bravo, Caleb Class, Irene Ganan-Gomez, Rashmi Kanagal-Shamanna, Koji Sasaki, Guillaume Richard-Carpentier, Kiran Naqvi, Yue Wei, Hui Yang, Kelly A. Soltysiak, Kelly Chien, Carlos Bueso-Ramos, Kim-Anh Do, Hagop Kantarjian, Guillermo Garcia-Manero
Caleb Class

Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy, Irene Ganan-Gomez, Hui Yang, Feiyang Ma, Guillermo Montalban-Bravo, Natthakan Thongon, Valentina Marchica, Guillaume Richard-Carpentier, Kelly Chien, Ganiraju Manyam, Feng Wang, Ana Alfonso, Shuaitong Chen, Caleb Class, Rashmi Kanagal-Shamanna, Justin P. Ingram, Yamini Ogoti, Ashley Rose, Sanam Loghavi, Pamela Lockyer, Benedetta Cambo, Muharrem Muftuoglu, Sarah Schneider, Vera Adema, Michael McLellan, John Garza, Matteo Marchesini, Nicola Giuliani, Matteo Pellegrini, Jing Wang, Jason Walker, Ziyi Li, Koichi Takahashi, Joel D. Leverson, Carlos Bueso-Ramos, Michael Andreeff, Karen Clise-Dwyer, Guillermo =Garcia-Manero, Simona Colla
Scholarship and Professional Work – COPHS

Type I Interferon Upregulation and Deregulation of Genes Involved in Monopoiesis in Chronic Myelomonocytic Leukemia, Guillermo Montalban-Bravo, Faezeh Darbaniyan, Rashmi Kanagal-Shamanna, Irene Ganan-Gomez, Caleb Class, Caleb Class, Koji Sasaki, Kiran Naqvi, Yue Wei, Hui Yang, Kelly Soltysiak, Kelly Chien, Carlos Bueso-Ramos, Kim-Anh Do, Hagop Kantarjian, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS

Evolutionary Action Score Identifies a Subset of TP53 Mutated Myelodysplastic Syndrome with Favorable Prognosis, Rashmi Kanagal-Shamanna, Guillermo Bravo, Panagiotis Katsonis, Koji Sasaki, Caleb Class, Christopher Benton, Elias Jabbour, Kelly Chien, Rajyalakshmi Luthra, Carlos Bueso-Ramos, Tapan Kadia, Michael Andreeff, Nicholas Short, Naval Daver, Mark Routbort, Joseph Khoury, Keyur Patel, Irene Ganan-Gomez, Yue Wei, Gautam Borthakur, Farhad Ravandi, Kim-Anh Do, Kelly Soltysiak, Olivier Lichtarge, L. Medeiros, Hagop Kantarjian, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS

Hypomethylating Agents Do Not Alter Novel Splicing Events in Myeloid Neoplasms, Hussein Abbas, Feng Wang, Yue Wei, Hui Yang, Guillermo Bravo, Rashmi Kanagal-Shamanna, Caleb Class, Faezeh Darbaniyan, Jianhua Zhang, Andy Futreal, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS

Outcomes of Acute Myeloid Leukemia with Myelodysplasia Related Changes depend on diagnostic criteria and therapy, Guillermo Montalban-Bravo, Rashmi Kanagal-Shamanna, Caleb Class, Koji Sasaki, Farhad Ravandi, Jorge Cortes, Naval Daver, Koichi Takahashi, Nicholas Short, Courtney DiNardo, Elias Jabbour, Gautam Borthakur, Kiran Naqvi, Ghayas Issa, Marina Konopleva, Joseph Khoury, Mark Routbort, Sherry Pierce, Kim Anh, Carlos Bueso-Ramos, Keyur Patel, Hagop Kantarjian, Guillermo Garcia-Manero, Tapan Kadia
Scholarship and Professional Work – COPHS

Transcriptomic analysis implicates necroptosis in disease progression and prognosis in myelodysplastic syndromes, Guillermo Montalban-Bravo, Caleb Class, Irene Ganan-Gomez, Rashmi Kanagal-Shamanna, Koji Sasaki, Guillaume Richard-Carpentier, Kiran Naqvi, Yue Wei, Hui Yang, Kelly A. Soltysiak, Kelly Chien, Carlos Bueso-Ramos, Kim-Anh Do, Hagop Kantarjian, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS

Genomic context and TP53 allele frequency define clinical outcomes in TP53-mutated myelodysplastic syndromes, Guillermo Montalban-Bravo, Rashmi Kanagal-Shamanna, Christopher B. Benton, Caleb A. Class, Kelly S. Chien, Koji Sasaki ,, Kiran Naqvi, Yesid Alvarado, Tapan M. Kadia, Farhad Ravandi, Naval Daver, Koichi Takahashi, Elias Jabbour, Gautham Borthakur, Naveen Pemmaraju, Marina Konopleva, Kelly A. Soltysiak, Sherry R. Pierce, Carlos E. Bueso-Ramos, Keyur P. Patel, Hagop Kantarjian, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS

Long-Term Follow up of a Randomized Phase 2 Study of Low-Dose Decitabine Versus Low-Dose Azacitidine in Lower-Risk Myelodysplastic Syndromes, Guillermo Montalban-Bravo, Elias Jabbour, Caleb Class, Nicholas Short, Rashmi Kanagal-Shamanna, Tapan Kadia, Gautam Borthakur, Naveen Pemmaraju, Koji Sasaki, Zeev Estrov, Jorge Cortes, Farhad Ravandi, Yesid Alvarado, Rami Komrokji, Mikkael Sekeres, David Steensma, Amy DeZern, Gail Roboz, Hui Yang, Hagop Kantarjian, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS

Genomic Context and TP53 Allele Frequency Define Prognostic Subgroups and Response Outcomes in TP53 Mutated Myelodysplastic Syndromes, Guillermo Montalban-Bravo, Rashmi Kanagal-Shamanna, Christopher Benton, Caleb Class, Kelly Chien, Koji Sasaki, Kiran Naqvi, Yesid Alvarado, Tapan Kadia, Farhad Ravandi, Jorge Cortes, Naval Daver, Koichi Takahashi, Courtney DiNardo, Elias Jabbour, Gautam Borthakur, Naveen Pemmaraju, Marina Konopleva, Sherry Pierce, Carlos Bueso-Ramos, Michael Andreeff, Keyur Patel, Hagop Kantarjian, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS

Loss of EZH2 Protein Expression in Myelodysplastic Syndrome Correlates with EZH2 Mutation and Portends a Worse Outcome, Ali Sakhdari, Caleb Class, Guillermo Montalban-Bravo, Koji Sasaki, Carlos Bueso-Ramos, Keyur Patel, Joseph Khoury, Hagop Kantarjian, Guillermo Garcia-Manero, L. Medeiros, Rashmi Kanagal-Shamanna
Scholarship and Professional Work – COPHS

Transcriptomic Analysis Implicates Necroptosis in Disease Progression and Prognosis in Myelodysplastic Syndromes, Guillermo Montalban-Bravo, Caleb Class, Irene Ganan-Gomez, Rashmi Kanagal-Shamanna, Koji Sasaki, Guillaume Richard-Carpentier, Kiran Naqvi, Yue Wei, Hui Yang, Kelly Soltysiak, Kelly Chien, Carlos Bueso-Ramos, Kim-Anh Do, Hagop Kantarjian, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS

Evolutionary Action (EA) Score of TP53 Mutations Defines Prognostic Subsets within TP53 Mutated Myelodysplastic Syndromes and Acute Myeloid Leukemia, Rashmi Kanagal-Shamanna, Guillermo Montalban-Bravo, Caleb Class, Koji Sasaki, Christopher Benton, Kelly Soltysiak, Elias Jabbour, Tapan Kadia, Carlos Bueso-Ramos, Keyur Patel, Mark Routbort, Irene Ganan-Gomez, Yue Wei, Gautam Borthakur, Farhad Ravandi, Kim-Anh Do, L. Medeiros, Hagop Kantarjian, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS

KDM6B Overexpression and TET2 Deficiency Cooperatively Drive Development of Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia-like Phenotype in Mice, Yue Wei, Hong Zheng, Naran Bao, Rashmi Kanagal-Shamanna, Caleb Class, Hui Yang, Guillermo Bravo, Irene Ganan-Gomez, Kelly Soltysiak, Kim-Ann Do, Simona Colla, Carlos Bueso-Ramos, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS