Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy, Irene Ganan-Gomez, Hui Yang, Feiyang Ma, Guillermo Montalban-Bravo, Natthakan Thongon, Valentina Marchica, Guillaume Richard-Carpentier, Kelly Chien, Ganiraju Manyam, Feng Wang, Ana Alfonso, Shuaitong Chen, Caleb Class, Rashmi Kanagal-Shamanna, Justin P. Ingram, Yamini Ogoti, Ashley Rose, Sanam Loghavi, Pamela Lockyer, Benedetta Cambo, Muharrem Muftuoglu, Sarah Schneider, Vera Adema, Michael McLellan, John Garza, Matteo Marchesini, Nicola Giuliani, Matteo Pellegrini, Jing Wang, Jason Walker, Ziyi Li, Koichi Takahashi, Joel D. Leverson, Carlos Bueso-Ramos, Michael Andreeff, Karen Clise-Dwyer, Guillermo =Garcia-Manero, Simona Colla
Scholarship and Professional Work – COPHS

KDM6B Overexpression and TET2 Deficiency Cooperatively Drive Development of Myelodysplastic Syndrome and Chronic Myelomonocytic Leukemia-like Phenotype in Mice, Yue Wei, Hong Zheng, Naran Bao, Rashmi Kanagal-Shamanna, Caleb Class, Hui Yang, Guillermo Bravo, Irene Ganan-Gomez, Kelly Soltysiak, Kim-Ann Do, Simona Colla, Carlos Bueso-Ramos, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS

KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice., Yue Wei, Hong Zheng, Naran Bao, Shan Jiang, Carlos Bueso-Ramos, Joseph Khoury, Caleb Class, Yue Lu, Kevin Lin, Hui Yang, Irene Ganan-Gomez, Daniel Starczynowski, Daniel Starczynowski, Kim Anh, Simona Colla, Guillermo Garcia-Manero
Scholarship and Professional Work – COPHS

Overexpression of Histone Demethylase KDM6B in the Hematopoietic Compartment Promotes the Effect of Innate Immune Activation and Results in Myelodysplastic Syndrome (MDS)-like Phenotype in Mice, Yue Wei, Guillermo Garcia-Manero, Hong Zheng, Yu Jia, Naran Bao, Shan Jiang, Joseph Khoury, Caleb Class, Simona Colla, Carlos Bueso-Ramos
Scholarship and Professional Work – COPHS