Document Type

Article

Publication Date

2009

Publication Title

Brain Research

First Page

68

Last Page

73

DOI

http://dx.doi.org/10.1016/j.brainres.2008.12.058

Abstract

Lesions of the insular cortex (IC) attenuate acquisition of conditioned taste aversions (CTAs). We have suggested that this impairment is the expected consequence of a failure of IC-lesioned (ICX) rats to recognize unfamiliar taste stimuli as novel. That is, ICX rats treat novel taste stimuli as if they are familiar and as a result show a latent inhibition-like retardation of learning. This account anticipates that ICX rats should acquire CTAs at the same slow rate as normal rats that are familiar with the taste stimulus. The present experiment confirmed this hypothesis in a design that compared CTA acquisition in normal and ICX rats following either extensive taste familiarization or no taste familiarization prior to conditioning.

Rights

This is a post-print version of an article originally published in Brain Research, 2009, Volume 1259.

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The version of record is available through: Elsevier.

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