A Randomized, Controlled Trial of Catheter-Related Infectious Event Rates Using Antibiotic-Impregnated Catheters Versus Conventional Catheters in Pediatric Cardiovascular Surgery Patients

Authors

Elaine G. Cox
Chad A. Knoderer, Butler UniversityFollow
Aimee Jennings
John W. Brown
Mark D. Rodefeld
Scott G. Walker
Mark W. Turrentine

Document Type

Article

Publication Date

2013

Publication Title

Journal of Pediatric Infectious Diseases Society

First Page

67

Last Page

70

DOI

http://dx.doi.org/10.1093/jpids/pis066

Abstract

We conducted a randomized, controlled clinical trial to determine whether a difference in catheter-associated blood stream infection (CABSI) incidence existed between children who underwent cardiac surgery and had a central venous catheter impregnated with minocycline and rifampin versus those who had a conventional, nonimpregnated catheter after cardiac surgery. Due to a lower number of infections than expected, the study was terminated early. Among 288 evaluable patients, the rates of CABSI and line-related complications were similar between the 2 groups.

Rights

This is a post-print version of an article originally published in Journal of Pediatric Infectious Diseases,2013, Volume 2, Issue 1.. The version of record is available at Oxford Journals.

Recommended Citation

Cox, Elaine G.; Knoderer, Chad A.; Jennings, Aimee; Brown, John W.; Rodefeld, Mark D.; Walker, Scott G.; and Turrentine, Mark W., "A Randomized, Controlled Trial of Catheter-Related Infectious Event Rates Using Antibiotic-Impregnated Catheters Versus Conventional Catheters in Pediatric Cardiovascular Surgery Patients" (2013). Scholarship and Professional Work – COPHS. 58.
https://digitalcommons.butler.edu/cophs_papers/58