Document Type
Article
Publication Date
2013
Publication Title
Journal of Pediatric Pharmacology and Therapy
First Page
63
Last Page
66
DOI
http://dx.doi.org/10.5863/1551-6776-18.1.63
Abstract
A 14-year-old male with bilateral above-the-knee amputations presented to our hospital for treatment of a skin and soft-tissue infection. We report the experience of vancomycin and gentamicin therapy in this patient. Because these medications require weight-based dosages and pharmacokinetic monitoring of serum levels, it was necessary to obtain peak and trough levels of the two drugs in order to determine the pharmacokinetic differences in this patient compared to those in an adolescent male without amputations. To our knowledge, this is the first report describing pharmacokinetic differences in an adolescent amputee.
Rights
This article was archived with permission from Pediatric Pharmacy Advocacy Group, all rights reserved. Document also available from Journal of Pediatric Pharmacology and Therapy.
Recommended Citation
Nichols, Kristen R.; Edison, Kari M.; Rosenbaum, Michelle D.; and Knoderer, Chad A., "Vancomycin and Gentamicin Pharmacokinetic Alterations in an Adolescent Amputee" (2013). Scholarship and Professional Work – COPHS. 69.
https://digitalcommons.butler.edu/cophs_papers/69