Date of Award

2017

Degree Type

Thesis

Degree Name

Honors Thesis

Department

Pharmacy

First Advisor

Kendra M. Damer

Second Advisor

Chad Knoderer

Abstract

Mumps outbreaks continue to transpire across the United States despite the available MMR (Measles-Mumps-Rubella) vaccine and seemingly high vaccination rates. There is limited evidence surrounding the management, impact, and prevention of mumps outbreaks. In particular, there are currently no formal recommendations from the CDC (Centers for Disease Control and Prevention) regarding the administration of additional doses of the MMR vaccine during a mumps outbreak. Furthermore, there are unanswered questions of possible waning of vaccine-induced mumps immunity and the impact of a third dose of the MMR vaccine to assist in mumps outbreak control. Existing studies suggest that administration of the MMR vaccine during a mumps outbreak may decrease the attack rate and number of mumps cases. This study will characterize mumps antibody titer levels of pharmacy students obtained before and after a university mumps outbreak. The current study will also assess for evidence of possible waning of vaccine-induced mumps immunity in pharmacy student subjects.

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