Biology
Appetite Suppressing Effects of Nicotine on Caenorhabditis Elegans Chemotaxis to E. Coli
Document Type
Oral Presentation
Location
Indianapolis, IN
Start Date
10-4-2015 9:45 AM
End Date
10-4-2015 10:45 AM
Sponsor
Robert Grammer (Belmont University)
Description
Nicotine has been shown to cause appetite suppressing effects in humans. Studies have shown that nicotine has a similar effect on C. elegans as it does to humans including response to nicotine. C. elegans are a great model organism of study, demonstrated by their small genome size, simple reproduction, and ease of maintenance. They are multicellular, eukaryotic nematodes that share many genetic similarities to humans. This relation will be used to study the effects nicotine has on C. elegans chemotaxis to E. coli. The average attraction of C. elegans free of nicotine will be compared to C. elegans treated with nicotine. The hypothesis being investigated is that nicotine will suppress chemotaxis of C. elegans towards its food source of E. coli OP50.
Appetite Suppressing Effects of Nicotine on Caenorhabditis Elegans Chemotaxis to E. Coli
Indianapolis, IN
Nicotine has been shown to cause appetite suppressing effects in humans. Studies have shown that nicotine has a similar effect on C. elegans as it does to humans including response to nicotine. C. elegans are a great model organism of study, demonstrated by their small genome size, simple reproduction, and ease of maintenance. They are multicellular, eukaryotic nematodes that share many genetic similarities to humans. This relation will be used to study the effects nicotine has on C. elegans chemotaxis to E. coli. The average attraction of C. elegans free of nicotine will be compared to C. elegans treated with nicotine. The hypothesis being investigated is that nicotine will suppress chemotaxis of C. elegans towards its food source of E. coli OP50.