Chemistry
Using GC-EGA to Analyze Nicotine N-oxide in Order to Explain Low Nicotine Concentrations in E-cigarette Liquids
Document Type
Oral Presentation
Location
Indianapolis, IN
Subject Area
Chemistry
Start Date
13-4-2018 2:00 PM
End Date
13-4-2018 2:45 PM
Sponsor
Anne Wilson (Butler University)
Description
Gas chromatography – evolved gas analysis (GC-EGA) was used to analyze e-cigarette liquids. Previous analyses of e-cigarette liquids have shown that the determined concentration of nicotine is lower than the advertised concentration. A possible explanation for this phenomenon is that the nicotine in the liquids is being oxidized to nicotine N-oxide by exposure to air, resulting in lower concentration of nicotine. This study focused on analyzing samples of microwave-rearranged nicotine N-oxide. Using GC-EGA, a calibration curve was generated for N-oxide concentration, which will be used to explain the low concentrations of nicotine in e-cigarette liquids.
Using GC-EGA to Analyze Nicotine N-oxide in Order to Explain Low Nicotine Concentrations in E-cigarette Liquids
Indianapolis, IN
Gas chromatography – evolved gas analysis (GC-EGA) was used to analyze e-cigarette liquids. Previous analyses of e-cigarette liquids have shown that the determined concentration of nicotine is lower than the advertised concentration. A possible explanation for this phenomenon is that the nicotine in the liquids is being oxidized to nicotine N-oxide by exposure to air, resulting in lower concentration of nicotine. This study focused on analyzing samples of microwave-rearranged nicotine N-oxide. Using GC-EGA, a calibration curve was generated for N-oxide concentration, which will be used to explain the low concentrations of nicotine in e-cigarette liquids.