Chemistry

Using GC-EGA to Analyze Nicotine N-oxide in Order to Explain Low Nicotine Concentrations in E-cigarette Liquids

Presenter Information

Cory Wuerch, Butler University

Document Type

Oral Presentation

Location

Indianapolis, IN

Subject Area

Chemistry

Start Date

13-4-2018 2:00 PM

End Date

13-4-2018 2:45 PM

Description

Gas chromatography – evolved gas analysis (GC-EGA) was used to analyze e-cigarette liquids. Previous analyses of e-cigarette liquids have shown that the determined concentration of nicotine is lower than the advertised concentration. A possible explanation for this phenomenon is that the nicotine in the liquids is being oxidized to nicotine N-oxide by exposure to air, resulting in lower concentration of nicotine. This study focused on analyzing samples of microwave-rearranged nicotine N-oxide. Using GC-EGA, a calibration curve was generated for N-oxide concentration, which will be used to explain the low concentrations of nicotine in e-cigarette liquids.

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Apr 13th, 2:00 PM Apr 13th, 2:45 PM

Using GC-EGA to Analyze Nicotine N-oxide in Order to Explain Low Nicotine Concentrations in E-cigarette Liquids

Indianapolis, IN

Gas chromatography – evolved gas analysis (GC-EGA) was used to analyze e-cigarette liquids. Previous analyses of e-cigarette liquids have shown that the determined concentration of nicotine is lower than the advertised concentration. A possible explanation for this phenomenon is that the nicotine in the liquids is being oxidized to nicotine N-oxide by exposure to air, resulting in lower concentration of nicotine. This study focused on analyzing samples of microwave-rearranged nicotine N-oxide. Using GC-EGA, a calibration curve was generated for N-oxide concentration, which will be used to explain the low concentrations of nicotine in e-cigarette liquids.