Document Type

Article

Publication Date

2009

Publication Title

Brain Research

First Page

135

Last Page

142

DOI

http://dx.doi.org/10.1016/j.brainres.2009.08.051

Abstract

The current study assessed the influence of excitotoxic lesions of the insular cortex (IC) on tastepotentiated odor aversion (TPOA) learning. Water-deprived rats initially received a single odortoxicosis or odor/taste-toxicosis pairing and were subsequently tested, in separate trials, with the odor and the taste stimulus. Indicating TPOA, neurologically intact rats conditioned with the odor/taste compound stimulus acquired significantly stronger odor aversions than normal rats conditioned with the odor stimulus. IC lesions disrupted TPOA, conditioned taste aversion and taste neophobia. The finding that taste did not potentiate odor aversion learning in the IC lesioned rats provides support for the “within-compound association” analysis but is inconsistent with the “sensory and-gate” account of TPOA learning.

Rights

This is a post-print version of an article originally published in Brain Research, 2009, Volume 1297.

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The version of record is available through: Elsevier.

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