Document Type
Article
Publication Date
2009
Publication Title
Brain Research
First Page
52
Last Page
60
DOI
http://dx.doi.org/10.1016/j.brainres.2009.07.033
Abstract
Intake of an unconditionally preferred taste stimulus (e.g., saccharin) is reduced by contingent administration of a drug of abuse (e.g., morphine). We examined the influence of insular cortex (IC) lesions on morphine-induced suppression of an olfactory cue and two taste stimuli with different levels of perceived innate reward value. Two major findings emerged from this study. First, morphine suppressed intake of an aqueous odor as well as each taste stimulus in neurologically intact rats. Second, IC lesions disrupted morphine-induced suppression of the taste stimuli but not the aqueous odor cue. These results indicate that the perceived innate reward value of the CS is not a factor that governs drug-induced intake suppression.
Rights
This is a post-print version of an article originally published in Brain Research, 1292, Volume 1292.
.The version of record is available through: Elsevier.
Recommended Citation
Lin, Jian-You; Roman, Christopher T.; and Reilly, Steve, "Morphine-induced Suppression of Conditioned Stimulus Intake: Effects of Stimulus Type and Insular Cortex Lesions" (2009). Scholarship and Professional Work – COPHS. 166.
https://digitalcommons.butler.edu/cophs_papers/166