Biology & Sustainability
Event Title
The Effect of Tea Polyphenols as Telomerase Inhibitors in Cancerous HeLa Cells
Document Type
Oral Presentation
Location
Indianapolis, IN
Subject Area
Biology & Sustainability
Start Date
11-4-2014 1:15 PM
End Date
11-4-2014 2:45 PM
Sponsor
Philip Villani (Butler University)
Description
Inhibition of telomerase in cancerous cells has been heavily researched since telomerase helps dictate cancer's proliferation and growth. As polyphenolics have shown to inhibit telomerase activity, cancer is being tested with foods high in phenolic content. In this experiment, both green and black tea polyphenols were extracted and applied to cancerous HeLa cells at various concentrations. Signs of apoptosis and telomerase activity were gauged using direct observation, immunofluorescent staining, Western Blotting, and telomerase assays.
The Effect of Tea Polyphenols as Telomerase Inhibitors in Cancerous HeLa Cells
Indianapolis, IN
Inhibition of telomerase in cancerous cells has been heavily researched since telomerase helps dictate cancer's proliferation and growth. As polyphenolics have shown to inhibit telomerase activity, cancer is being tested with foods high in phenolic content. In this experiment, both green and black tea polyphenols were extracted and applied to cancerous HeLa cells at various concentrations. Signs of apoptosis and telomerase activity were gauged using direct observation, immunofluorescent staining, Western Blotting, and telomerase assays.