Pharmacy, Health Sciences & Exercise Science
The Effect of Body Composition, Strength, and Fitness on Glucose Clearance
Document Type
Oral Presentation
Location
Indianapolis, IN
Subject Area
Pharmacy, Health Sciences & Exercise Science
Start Date
11-4-2014 10:15 AM
End Date
11-4-2014 11:45 AM
Sponsor
Bryant Stamford (Hanover College)
Description
The purpose of this study was to determine the impact of a variety of factors on glucose clearance from the bloodstream. Specifically, this study examined the relationships between lean body mass, body fat, muscular strength, grip strength, VO2max, fasted blood glucose concentration and glucose clearance, in order to determine which variable(s) exerted the greatest effect.This study received approval from the Hanover College Institutional Review Board with regard to the use of human subjects.
Methods: Twenty male subjects volunteered to participate. Lean body mass and body fat were measured through hydrostatic weighing. Muscular strength was assessed by a 1-R M bench press. Grip strength was measured with a maximal contraction on a hand grip dynamometer. VO2max was estimated from the Bruce protocol treadmill test. Fasted blood glucose concentration and total glucose clearance were measured via a standard oral glucose tolerance test (OGTT) administered following a minimal 12-hour fast. The OGTT required ingestion of 75 grams of glucose after which blood samples were obtained via the finger stick method at 15-minute intervals.
Results & Discussion: Data collection is ongoing at present. However, pilot data suggests an inverse relationship between absolute body fat and percent body fat and total glucose clearance. There was the suggestion of a positive relationship for muscular strength and VO2max and total glucose clearance. A less-pronounced positive relationship was indicated for lean body mass and grip strength and fasted blood glucose concentration and total glucose clearance.
The Effect of Body Composition, Strength, and Fitness on Glucose Clearance
Indianapolis, IN
The purpose of this study was to determine the impact of a variety of factors on glucose clearance from the bloodstream. Specifically, this study examined the relationships between lean body mass, body fat, muscular strength, grip strength, VO2max, fasted blood glucose concentration and glucose clearance, in order to determine which variable(s) exerted the greatest effect.This study received approval from the Hanover College Institutional Review Board with regard to the use of human subjects.
Methods: Twenty male subjects volunteered to participate. Lean body mass and body fat were measured through hydrostatic weighing. Muscular strength was assessed by a 1-R M bench press. Grip strength was measured with a maximal contraction on a hand grip dynamometer. VO2max was estimated from the Bruce protocol treadmill test. Fasted blood glucose concentration and total glucose clearance were measured via a standard oral glucose tolerance test (OGTT) administered following a minimal 12-hour fast. The OGTT required ingestion of 75 grams of glucose after which blood samples were obtained via the finger stick method at 15-minute intervals.
Results & Discussion: Data collection is ongoing at present. However, pilot data suggests an inverse relationship between absolute body fat and percent body fat and total glucose clearance. There was the suggestion of a positive relationship for muscular strength and VO2max and total glucose clearance. A less-pronounced positive relationship was indicated for lean body mass and grip strength and fasted blood glucose concentration and total glucose clearance.