Chemistry
Iron-Catalyzed Synthesis of 3-Arylindoles: Annulation of Polymer Encapsulated Aryl Hydroxylamines with Alkynes
Document Type
Poster Presentation
Location
Indianapolis, IN
Subject Area
Chemistry
Start Date
11-4-2014 8:30 AM
End Date
11-4-2014 9:30 AM
Sponsor
Angus Lamar (Hanover College)
Description
3-Phenylindole was prepared in moderate to good yield from the thermal reaction of an alkyne (phenylacetylene) and a polymer-encapsulated aryl hydroxylamine (PhNHOH) catalyzed by 10 mol% iron (II) phthalocyanine [Fe(Pc)]. In the study, the aryl hydroxylamine was successfully encapsulated within polystyrene to serve as a method of slow release into the reaction medium. A variety of catalysts and reaction conditions were tested, and our progress will be reported.
Iron-Catalyzed Synthesis of 3-Arylindoles: Annulation of Polymer Encapsulated Aryl Hydroxylamines with Alkynes
Indianapolis, IN
3-Phenylindole was prepared in moderate to good yield from the thermal reaction of an alkyne (phenylacetylene) and a polymer-encapsulated aryl hydroxylamine (PhNHOH) catalyzed by 10 mol% iron (II) phthalocyanine [Fe(Pc)]. In the study, the aryl hydroxylamine was successfully encapsulated within polystyrene to serve as a method of slow release into the reaction medium. A variety of catalysts and reaction conditions were tested, and our progress will be reported.